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I was diagnosed with HIV in 2003. This is a good medicine, have been on it for several years already.
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There were no significantly different effects at the other 3TC concentrations (Fig.
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Strategies for the optimal sequencing of antiretroviral drugs toward overcoming and preventing drug resistance.
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Hepatitis C-Related Hepatocellular Carcinoma in the United States: Influence of Ethnic Status.
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When the viruses are released from the cell they infect all the other healthy cells that are spread throughout the body and so HIV spreads to new uninfected cells.
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Main disadvantages of nucleos(t)ide analogues are the long duration of treatment and the risk of developing resistance.
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The high rate of lamivudine resistance which reaches 56% and 70% after 3 and 4 years of treatment, respectively, is now of lesser concern, since equally well tolerable alternatives like adefovir (), entecavir () or telbivudine (), or their combinations are available which display lower rates of viral resistance and a different mutational profile.
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As experience with PEP continues to accumulate, it has become increasingly clear that tolerability is one of the most important factors in selecting a PEP regimen, especially when the source person is not available for testing and the patient will need to complete the full 28-day course.
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Review The Emerging Profile of Cross-Resistance among the Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors.
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However, only three of 10 interpretation systems showed significant independent prediction of the 12- or 24-week response in a multivariable model that included characteristics of patient history, baseline features such as HIV-1 RNA levels and number of resistance mutations, and characteristics of the salvage regimen (number of new and total number of antiretroviral drugs and use of a new drug class).
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Determination of the stage of liver disease is important in guiding antiviral therapy decisions and need for surveillance.
Lamivudine (Epivir) is used in combination with other medications to treat human immunodeficiency virus (HIV) infection in patients with acquired immunodeficiency syndrome (AIDS).
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At any time that exposed persons test positive for HCV RNA, the clinician should refer for medical management and possible treatment by a clinician with experience in treating HCV.